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Title:
TNF-α阻害剤としての環式ヒドラジン誘導体
Document Type and Number:
Japanese Patent JP3913983
Kind Code:
B2
Abstract:
Hydrazine derivatives and their pharmaceutically acceptable salts useful for the treatment of inflammatory and autoimmune diseases, osteoarthritis, respiratory diseases, tumors, cachexia, cardiovascular disease, fever, hemorrhage, and sepsis.

Inventors:
Broadhurst, Michael John
Johnson, William Henry
Walter, Daryl Simon
Application Number:
JP2000588147A
Publication Date:
May 09, 2007
Filing Date:
December 02, 1999
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D233/38; A61K31/4166; A61K31/4184; A61K31/433; A61K31/438; A61K31/4439; A61K31/496; A61K31/513; A61K31/517; A61K31/519; A61K31/53; A61K31/549; A61P7/00; A61P7/04; A61P9/00; A61P9/10; A61P11/00; A61P19/02; A61P29/00; A61P31/04; A61P35/00; A61P37/00; A61P43/00; C07D233/34; C07D233/80; C07D233/84; C07D233/86; C07D233/96; C07D235/02; C07D239/22; C07D239/54; C07D239/96; C07D241/08; C07D249/12; C07D251/34; C07D253/06; C07D285/10; C07D285/18; C07D401/06; C07D471/04; C07D471/10; C07D487/04; C07D495/04
Foreign References:
WO1999001428A1
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda