Title:
CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
Document Type and Number:
Japanese Patent JP2022191236
Kind Code:
A
Abstract:
To provide prodrugs and pharmaceutical compositions containing the prodrugs.SOLUTION: A prodrug has the following formula, where R5 independently represent a drug moiety and binds to L5 through N of the drug moiety or binds to L5 through O of the drug moiety; the drug moiety independently represent a monovalent radical of an anti-infective drug or an anti-cancer drug; and the anti-infective drug is an anti-parasitic drug, anti-malarial drug, or anti-bacterial drug.SELECTED DRAWING: Figure 1
Inventors:
Adam Earl Renslow
Erica M Be Lauter Basser
Sean Dee Fontaine
Benjamin Be Spangler
James A Wells
Erica M Be Lauter Basser
Sean Dee Fontaine
Benjamin Be Spangler
James A Wells
Application Number:
JP2022147665A
Publication Date:
December 27, 2022
Filing Date:
September 16, 2022
Export Citation:
Assignee:
The Regents of the University of California
International Classes:
C07D323/02; A61K31/357; A61K31/37; A61K31/403; A61K31/4192; A61K31/427; A61K31/438; A61K31/444; A61K31/4709; A61K31/4745; A61K31/475; A61K31/496; A61K31/4985; A61K31/519; A61K31/665; A61K31/695; A61K31/7068; A61K31/7072; A61K31/7076; A61K38/05; A61K45/00; A61K47/54; A61K47/60; A61K47/65; A61P31/00; A61P31/04; A61P33/00; A61P33/06; A61P35/00; A61P35/02; A61P43/00; C07D405/12; C07D405/14; C07D407/12; C07D407/14; C07D417/12; C07D417/14; C07D487/04; C07D491/113; C07D491/22; C07D493/18; C07D519/00; C07F9/655; C07F9/6558; C07H19/06; C07H19/16; C07H19/19
Domestic Patent References:
| JP2021001260A | 2021-01-07 | |||
| JP2004535436A | 2004-11-25 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office