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Title:
医薬として有用なシクロペンタン(エン)ヘプテンまたはヘプタン酸およびその誘導体
Document Type and Number:
Japanese Patent JP3778563
Kind Code:
B2
Abstract:
The invention relates to 7-[5-hydroxy-2-(hydroxyhydrocarbyl or heteroatom-substituted hydroxy hydrocarbyl)-3-hydroxy-cyclopentyl(enyl)] heptanoic or heptenoic acids and derivatives of said acids, wherein one or more of said hydroxy groups are replaced by an ether group. The compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma.

Inventors:
Burke, Robert M
Application Number:
JP51804295A
Publication Date:
May 24, 2006
Filing Date:
December 06, 1994
Export Citation:
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Assignee:
ALLERGAN,INCORPORATED
International Classes:
C07C405/00; A61K31/557; A61K31/5575; A61K31/5585; A61K31/66; A61P27/02; A61P27/06; C07D213/24; C07D307/38; C07D333/26
Domestic Patent References:
JP52010243A
JP50030850A
JP3058930A
Other References:
Prostaglandins and Medicine, 1981年,6(4), p.345-357
Attorney, Agent or Firm:
Aoyama Aoi
Yasuo Shibata