Title:
アルコール使用および断酒のバイオマーカーとしてのＤＮＡメチル化状態
Document Type and Number:
Japanese Patent JP6807833
Kind Code:
B2
Abstract:
This disclosure provides methods and materials for determining whether or not an individual is using alcohol, and also for determining whether or not the individual has stopped using alcohol.
Inventors:
Philipto Robert
Application Number:
JP2017515274A
Publication Date:
January 06, 2021
Filing Date:
May 28, 2015
Export Citation:
Assignee:
Philipto Robert
International Classes:
C12Q1/6806; C12N15/09; C12Q1/6813; C12Q1/6844; G01N33/53
Foreign References:
| US20120108444 | ||||
| US20120149589 |
Other References:
PHILIBERT, R.A., et al.,"The impact of recent alcohol use on genome wide DNA methylation signatures.",Frontiers in Genetics,2012年 4月,Vol.3,54(p.1-8)
LIU, Y., et al.,"Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation.",Epigenetics,2009年10月,Vol.4, No.7,pp.500-511
ZHANG, H., et al.,"Array-based profiling of DNA methylation changes associated with alcohol dependence.",Alcohol Clin Exp Res.,2013年 1月,Vol.37, Suppl. 1,pp.E108-E115
LIU, Y., et al.,"Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation.",Epigenetics,2009年10月,Vol.4, No.7,pp.500-511
ZHANG, H., et al.,"Array-based profiling of DNA methylation changes associated with alcohol dependence.",Alcohol Clin Exp Res.,2013年 1月,Vol.37, Suppl. 1,pp.E108-E115
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto