Title:
Drosophilamelanogaster中のリガンド依存性塩素イオンチャネルをコードするDNA分子
Document Type and Number:
Japanese Patent JP4769401
Kind Code:
B2
Abstract:
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Drosophila melanogaster ligand-gated ion channel proteins. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encoding Drosophila ligand-gated ion channel proteins, substantially purified forms of associated Drosophila ligand-gated ion channel proteins and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associated Drosophila melanogaster ligand-gated ion channel proteins, which will be useful as insecticides.
Inventors:
Curry, Doris F
Hirschberg, Birgit
Yuan, The Free
Chiang, Intson
Hirschberg, Birgit
Yuan, The Free
Chiang, Intson
Application Number:
JP2001564198A
Publication Date:
September 07, 2011
Filing Date:
February 26, 2001
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C12N15/09; C07H21/04; C07K14/435; C07K14/705; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/00; C12Q1/02
Other References:
J.Comp.Physiol.A.,1995,176(5),p.611-23
J.Biol.Chem.,1997,272(52),p.33167-74
J.Biol.Chem.,1997,272(52),p.33167-74
Attorney, Agent or Firm:
Yoshio Kawaguchi
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma
Mitsuru Inoue
Akio Ichiiri
Katsuma Osaki
Takamasa Soma