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Title:
DEFERASIROX DISPERSIBLE TABLET
Document Type and Number:
Japanese Patent JP2010031022
Kind Code:
A
Abstract:

To provide a dispersible tablet comprising, as an active ingredient effective as an iron chelating agent used in a patient requiring repeating blood transfusion, 4-[3, 5-bis(2-hydroxyphenyl)-[1, 2, 4] triazol-1-yl] benzoic acid (a compound I) or a pharmaceutically acceptable salt thereof, wherein the tablet provides a type of oral administration that is easy in administration to an adult and a child and can supply a pharmaceutically active daily dosage.

A dispersible tablet consists of a compound I in an amount of from 5 to 40 wt.% based on the total weight of the tablet, preferably containing (a) the compound I or the pharmaceutically acceptable salt thereof, and (b) at least one pharmaceutically acceptable vehicle suitable for production of the tablet, wherein the compound I or the pharmaceutically acceptable salt thereof is present in an amount of from 5 to 40 wt.% based on the total weight of the tablet.


Inventors:
DEFFEZ KARINE
CASSIERE JEAN-PIERRE
Application Number:
JP2009222652A
Publication Date:
February 12, 2010
Filing Date:
September 28, 2009
Export Citation:
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Assignee:
NOVARTIS AG
International Classes:
A61K31/4196; A61K9/00; A61K9/20; A61K31/41; A61P7/00; A61P39/04
Domestic Patent References:
JPH115735A1999-01-12
JP2000273045A2000-10-03
JP2002121133A2002-04-23
JP2000247879A2000-09-12
JP2000086503A2000-03-28
JP2000063269A2000-02-29
JP2000507601A2000-06-20
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Yasushi Ochiai