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Title:
デング熱1、2、3および4型又は抗原性キメラデング熱ウイルス1、2、3および4の3’-UTRにおいて30ヌクレオチド欠失を共通に含有するデング熱四価ワクチン
Document Type and Number:
Japanese Patent JP4977811
Kind Code:
B2
Abstract:
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3'-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.

Inventors:
Whitehead, Stephen S.
Murphy, Brian Earl.
Markov, Lewis
Fargout, Barry
Blaney, Joseph
Hanley, Kathryn
Application Number:
JP2004500777A
Publication Date:
July 18, 2012
Filing Date:
April 25, 2003
Export Citation:
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Assignee:
THE UNITED STATES OF AMERICA
International Classes:
C12N15/09; A61K31/7088; A61K35/76; A61K38/00; A61K39/12; A61K39/295; A61K39/42; A61P31/14; C07H21/00; C07H21/04; C12N7/00; C12N7/04; C12Q1/68; A61K39/00; A61K
Foreign References:
WO2001091790A1
Other References:
Am. J. Trop. Med. Hyg.,2001年,vol.65, no.5,pp.405-413
Am. J. Trop. Med. Hyg.,2001年,vol.65, no.5,pp.414-419
J. Virol.,2001年,vol.75, no.20,pp.9731-9740
Vaccine,2000年,vol.18, suppl.2,pp.44-47
Vaccine,2001年,vol.19, no.23-24,pp.3179-3188
Clin. Diagn. Virol.,1988年,vol.10, no.2-3,pp.173-179
J. Virol.,1996年,vol.70, no.6,pp.3930-3937
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Yutaka Nagata
Tsutomu Toyama



 
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