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Title:
DERIVATIVE HAVING PPAR(PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR) AGONISTIC ACTIVITY
Document Type and Number:
Japanese Patent JP2009215300
Kind Code:
A
Abstract:

To provide a compound useful as a PPAR agonist.

The compound is represented by formula (I) (wherein, the ring Q is a monocyclic aryl group that may be substituted or the like; Y1 is a single bond, -NR6- or the like; the ring A is a nonaromatic heterocyclic diyl or the like; formulae: -Y2 and Z1-are each a group represented by formula (II) or the like; in formula (II), R7, R8 and R9 are each a lower alkyl group or the like, n is an integer of 0 to 3, and Z1 is a single bond, O, S or NR9; the ring B is an aromatic carbocyclic diyl or the like; Y3 is a lower alkenylene group or the like; and Z2 is COOR3 or the like).


Inventors:
ITAI AKIKO
MUTO SUSUMU
TOKUYAMA TATSUMITSU
FUKAZAWA HIROSHI
OHARA TAKAFUMI
KATO TERUKAZU
Application Number:
JP2009100563A
Publication Date:
September 24, 2009
Filing Date:
April 17, 2009
Export Citation:
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Assignee:
IYAKU BUNSHI SEKKEI KENKYUSHO
SHIONOGI & CO
International Classes:
C07D211/34; A61K31/428; A61K31/445; A61K31/495; A61K31/496; A61K31/498; A61K31/506; A61K31/5377; A61K31/55; A61K31/551; A61P1/04; A61P1/18; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P15/00; A61P17/00; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P37/00; A61P43/00; C07D215/38; C07D241/04; C07D241/44; C07D277/20; C07D277/42; C07D277/82; C07D401/04; C07D403/04; C07D405/04; C07D405/14; C07D409/04; C07D413/04; C07D417/04; C07D417/14; C07D487/08; C07D513/04
Foreign References:
WO2007023882A12007-03-01
Attorney, Agent or Firm:
Kenichi Sugita
Hiromitsu Takayama



 
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