Title:
アザビシクロオクタンの誘導体、その製造方法及びそのジペプチジルペプチダーゼIVの阻害剤としての用途
Document Type and Number:
Japanese Patent JP5438028
Kind Code:
B2
Abstract:
Disclosed are new dicycloazaalkane derivates represented by general formula (I), preparation processes and pharmaceutical compositions containing them, and the uses for treatment especially for dipeptidyl peptidase inhibitor (DPP-IV), in which each substitute group of general formula (I) is as defined in specification.
Inventors:
Tan Pencho
Lynn Zian
Liu He Jin
Xiao Fuchin
Lee Lee
Yang Fan Long
Fu Chang Hong
One Lin
Shen Kowan Yuwan
Cowan Tonleans
Lynn Zian
Liu He Jin
Xiao Fuchin
Lee Lee
Yang Fan Long
Fu Chang Hong
One Lin
Shen Kowan Yuwan
Cowan Tonleans
Application Number:
JP2010543359A
Publication Date:
March 12, 2014
Filing Date:
May 20, 2008
Export Citation:
Assignee:
Jence Hansen Pharmaceutical Company Limited
International Classes:
C07D209/52; A61K31/403; A61K31/454; A61K31/5377; A61P3/10; C07D403/12
Domestic Patent References:
| JP2010516635A | ||||
| JP2006523190A | ||||
| JP2005511557A | ||||
| JP2009532391A | ||||
| JP2005350456A |
Foreign References:
| WO2006012396A1 | ||||
| US5736550 | ||||
| WO2006028961A1 | ||||
| WO1994000454A1 | ||||
| WO2007029086A1 |
Other References:
Barluenga,J. et al,Chemistry-A European Journal,1997年,Vol.3, No.8,p.1324-1336
MIHOVILOVIE,M.D. et al,ARKIVOC,2001年,Vol.2, No.2,p.28-33
BROWN,S.W. et al,Journal of the Chemical Society Perkin Transactions.1,1990年,Vol.4,p.1205-1209
BECKER,D.P. et al,Tetrahedron Letters,1993年,Vol.34, No.13,p.2087-2090
MIHOVILOVIE,M.D. et al,ARKIVOC,2001年,Vol.2, No.2,p.28-33
BROWN,S.W. et al,Journal of the Chemical Society Perkin Transactions.1,1990年,Vol.4,p.1205-1209
BECKER,D.P. et al,Tetrahedron Letters,1993年,Vol.34, No.13,p.2087-2090
Attorney, Agent or Firm:
Xie Takamine
Yasushi Sasaki
Yasushi Sasaki