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Title:
【発明の名称】大環状キレート化合物の抱合体と診断的テスト方法
Document Type and Number:
Japanese Patent JPH0720989
Kind Code:
B2
Abstract:
The invention is a chelate of formula I: ember selected from the group consisting of -NO2, -NH2, -NCS, -NHCOCH2-Z, with Z being a member selected from the group consisting of Br and I, -COOH; and -OCH2OOCH; and M is a metal ion selected from the group of elements consisting of Bi, Pb, Y, Cd, Hg, Al, Th, Sr, and Lanthanides. The invention also includes a chelate, wherein M is a copper ion and n is an integer from 2 to 5. The invention includes chelate conjugates of formula I and ligand conjugates of formula II: The invention also includes methods to use these compounds for treatment of cellular disorders and for diagnostic tests.

Inventors:
GANSOO OTSUTOO EI
BUREKUBIIRU MAATEIN AARU
MAAGAASHUTATSUTO MIHYAERU AA
Application Number:
JP50710589A
Publication Date:
March 08, 1995
Filing Date:
May 24, 1989
Export Citation:
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Assignee:
US COMMERCE (US)
International Classes:
A61K31/555; A61K49/00; A61K51/04; G01N33/532; A61K51/08; A61K51/10; A61P35/00; C07D257/02; C07F3/00; C07F3/08; C07F3/12; C07F5/00; C07F5/06; C07F7/24; C07F9/94; C07F13/00; C07F15/02; C07F15/06; C07K4/00; C07K14/00; C07K14/52; C07K14/54; C07K14/55; C07K14/575; C07K16/00; C07K16/44; G01N33/534; G01N33/574; (IPC1-7): C07K4/00; C07K16/44; G01N33/532
Domestic Patent References:
JPS6341468A1988-02-22
Attorney, Agent or Firm:
Nao Okuyama (2 outside)