Title:
【発明の名称】δ-ハイドロキシ-β-リジン誘導体およびその製造法
Document Type and Number:
Japanese Patent JP2605762
Kind Code:
B2
Abstract:
A compound of the formula wherein R<1> and R<4> are independently amino or an organic residue bonded through nitrogen, R<2> is hydrogen or alkyl which may be substituted, R<3> is hydrogen or a protecting group and R5 is hydroxyl which may be substituted or amino which may be substituted or salts thereof; with the proviso that when R<1> is amino, sorbylamino or hexanoylamino, R<2> is hydrogen or methyl, R<4> is amino which may be protected adn R<5> is hydroxyl or 2-amidinoethylamino, R<3> is a protecting group, and that when R<1> is amino, leucylamino, acetylamino or benzyloxycarbonylamino, R<3> is hydrogen, methyl or 2-tettrahydropyranyl, R<4> is amino, acetylamino or benzyloxycarbonylamino and R<5> is hydroxyl which may be substituted or amino which may be substituted, R<2> is alkyl which may be substituted, has antibacterial activities against drug-resistant bacteria and therefore can be useful as a chemotherapeutic drug for bacterial infections in mammals.
Inventors:
Masuya Kodai
Setsuo Harada
Natsukari Hideaki
Setsuo Harada
Natsukari Hideaki
Application Number:
JP30638287A
Publication Date:
April 30, 1997
Filing Date:
December 02, 1987
Export Citation:
Assignee:
Takeda GmbH
International Classes:
A61K31/16; A61K31/195; A61K31/22; A61K31/27; A61P31/04; C07C67/00; C07C229/26; C07C231/00; C07C231/02; C07C231/12; C07C233/45; C07C233/49; C07C237/06; C07C237/12; C07C237/22; C07C239/00; C07C257/14; C07C257/22; C07C271/54; C07C279/12; C07C279/14; C07C279/24; C07C311/32; C07C313/00; C07C317/44; C07C323/60; C07D209/48; C07D213/75; C07D233/54; C07D265/10; C07D295/12; C07D295/13; C07D295/195; C07D307/54; C07D309/30; C07D335/02; C07D339/06; C07D339/08; C07F7/18; C07F9/24; C07F9/44; (IPC1-7): C07C257/14; A61K31/22; A61K31/27; C07C257/22; C07C271/54
Domestic Patent References:
| JP5259112A | ||||
| JP816087B2 |
Attorney, Agent or Firm:
Tadao Asahina (1 person outside)