Title:
【発明の名称】高分解能および高処理量の分離のための、微細加工されたインゼクタおよびキャピラリ・アレイ・アセンブリ
Document Type and Number:
Japanese Patent JP2003519363
Kind Code:
A
Abstract:
The present invention concerns methods and apparatus for the high resolution, high output electrophoretic separation of molecules. In preferred embodiments, the methods and apparatus are of use for DNA sequencing. The apparatus comprises a hybrid device, comprising a microfabricated chip injector attached to an array of one or more capillaries. The chip injector is designed with incorporation and injector channels that precisely match the capillaries, to minimize or eliminate dead volume in the system. DNA sequencing runs of over 700 bases, with a run time of less than one hour, may be accomplished with the methods and apparatus disclosed herein.
Inventors:
Liu, Xiao Long
Application Number:
JP2001519106A
Publication Date:
June 17, 2003
Filing Date:
June 30, 2000
Export Citation:
Assignee:
Liu, Xiao Long
International Classes:
G01N27/62; B01L3/00; C12M1/00; C12N15/09; C12Q1/68; G01N21/64; G01N27/447; G01N33/50; G01N33/53; G01N33/566; G01N33/58; G01N37/00; (IPC1-7): G01N27/447; C12M1/00; C12N15/09; C12Q1/68; G01N21/64; G01N27/62; G01N33/50; G01N33/53; G01N33/566; G01N33/58; G01N37/00
Attorney, Agent or Firm:
Masaki Yamakawa