Title:
【発明の名称】ポルフォシアニン及びCNC-展開ポルフィリン
Document Type and Number:
Japanese Patent JPH10500942
Kind Code:
A
Abstract:
Compounds of the formula and the metalated forms and salts thereof; wherein n is an integer of 1-4; and wherein each Pi is independently a pyrrole residue of the formula wherein each Ria and Rib is independently a noninterfering substituent, and wherein each Zi is independently a covalent bond; or is a meso bridging group of the formula or is an N-meso bridging group of the formula=N--><--N=; or isa CC linkage of the formula or is a CNCCNC linkage of the formula wherein each Ric, Rid, Rie, Rif and Rig is independently a noninterfering substituent; or is a CNC linkage of the formula-CH=N-CH=-><-=CH-N=CH-wherein at least one Zi is said CNC linkage, are disclosed. These compounds are useful in photodynamic therapy and diagnosis. The metalated forms when the metal is paramagnetic are useful as MRI contrast agents.
Inventors:
Boyle, Ross W.
Tan, Han
Zee, Lily
Wije Sekera, Tilak
Dolphin, David
Tan, Han
Zee, Lily
Wije Sekera, Tilak
Dolphin, David
Application Number:
JP52719795A
Publication Date:
January 27, 1998
Filing Date:
April 26, 1995
Export Citation:
Assignee:
Quadra Logic Technologies Inc.
International Classes:
A61K31/40; A61K31/409; A61K31/555; A61K38/00; A61K39/395; A61K41/00; A61K49/00; A61K49/06; A61K51/00; A61K51/04; C12P21/08; A61P35/00; C07B59/00; C07D487/22; C07F5/00; C07F13/00; C07K16/00; (IPC1-7): C07D487/22; A61K31/40; A61K49/00; A61K51/00; C07F5/00; C07F13/00; C07K16/00
Attorney, Agent or Firm:
Asato Kato