Title:
【発明の名称】合成二価sLex含有ポリラクトサミン類および使用法
Document Type and Number:
Japanese Patent JP2001515912
Kind Code:
A
Abstract:
The present invention is directed to novel compositions and their use in the treatment of inflammatory responses. Specifically, the invention is directed to novel synthetic oligosaccharide constructs and their use to block lymphocyte binding to correspondent oligosaccharides on the endothelial surface, and thus reduce or otherwise ameliorate an undesired inflammatory response. The invention is further directed to the use of such constructs in other disease states characterized by selectin binding, such as bacterial infections and metastatic cancers.
Inventors:
Lenkonen, Ossi
Lenkonen, list
Lenkonen, list
Application Number:
JP2000510750A
Publication Date:
September 25, 2001
Filing Date:
September 04, 1998
Export Citation:
Assignee:
Grissim Osuke Yukyuu
International Classes:
A61K31/70; A61K31/702; A61K31/7028; A61K31/715; A61K31/726; A61P1/04; A61P11/00; A61P17/00; A61P19/02; A61P29/00; A61P31/00; A61P31/04; A61P35/04; C07H15/12; A61P37/06; C07H1/00; C07H7/02; C07H13/04; C07H17/04; C08B37/00; C12P19/04; C12P19/18; C12P19/26; C07H; (IPC1-7): C07H15/12; A61K31/702; A61K31/726; A61P1/04; A61P11/00; A61P19/02; A61P29/00; A61P31/00; A61P31/04; A61P35/04; A61P37/06; C08B37/00
Attorney, Agent or Firm:
Sota Asahina (1 person outside)