Title:
Development of the improved type new giant molecule transfer domain which has improved cell penetration ability, and a utilizing method for the same
Document Type and Number:
Japanese Patent JP6001082
Kind Code:
B2
Abstract:
The present invention relates to an improved macromolecule transduction domain (MTD), which facilitates permeating the cell membrane of a biologically active molecule, having enhanced cell permeability. Specifically, an improved MTD according to the present invention, compared to an existing MTD, can transmit various types of biologically active molecule from inside the body and inside a test tube more effectively, and thus can be effectively used in a method to genetically alter a biologically active molecule so as to have cell permeability or in a method to transport a biologically active molecule into a cell, or the like. Additionally, the improved MTD can be very useful in development of new drugs and incrementally modified drugs as uses of the improved MTD are possible in drug delivery systems, recombinant protein vaccines or DNA/RNA therapeutic agents, gene or protein therapies, and pharmacologically or medically useful protein production or medical, pharmacological and pharmaceutical compositions.
Inventors:
Shin, Kidoku
Lee, Kang Jin
Im sunny
Lee, Byung Kyu
Kim, John Ray
Lee, Kang Jin
Im sunny
Lee, Byung Kyu
Kim, John Ray
Application Number:
JP2014543424A
Publication Date:
October 05, 2016
Filing Date:
November 23, 2012
Export Citation:
Assignee:
Procell Therapeutics Incorporated
International Classes:
C07K7/00; A61K47/42; C07K19/00; C12N15/09
Domestic Patent References:
| JP2010516758A |
Attorney, Agent or Firm:
Patent Business Corporation Unias International Patent Office
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