Title:
DIAGNOSIS OF NANBV: POLYNUCLEOTIDE USEFUL FOR SCREENING HEPATITIS C VIRUS
Document Type and Number:
Japanese Patent JP3701754
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain a new polynucleotide capable of selectively hybridizing with the polynucleotide sequence of hepatitis C virus (HCV), thus useful as e.g. a probe for detectting HCV polynucleotide, and to be used for e.g. diagnosing hepatitis non-A non-B virus (NANBV).
SOLUTION: This new polynucleotide has a 10 or more nucleotides- consecutive sequence consisting of either chain of nucleotide sequences of formula I and formula II, being capable of selectively hybridizing with the polynucleotide sequence of HCV. This new polynucleotide is useful as a polynucleotide probe for detecting the polynucleotide of HCV, a PCR primer for amplifying the polynucleotide, etc., and enables infection diagnoses of NANBV. This new polynucleotide is obtained by preparing a cDNA library including a HCV cDNA sequence and by screening the library.
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Inventors:
Michael houghton
Qui-Rim Cho
George Quo
Jean Han
Michael S. Ardia
Emmy Jay. Weiner
Qui-Rim Cho
George Quo
Jean Han
Michael S. Ardia
Emmy Jay. Weiner
Application Number:
JP30570796A
Publication Date:
October 05, 2005
Filing Date:
October 30, 1996
Export Citation:
Assignee:
Chiron Corporation
International Classes:
C12N15/09; C07K14/18; C12N15/40; C12N15/51; C12Q1/68; C12Q1/70; G01N33/576; A61K39/00; C12R1/93; (IPC1-7): C12N15/09; C12Q1/68
Domestic Patent References:
| JP3171792B2 | ||||
| JP10113176A | ||||
| JP2656996B2 | ||||
| JP10000089A | ||||
| JP2662358B2 | ||||
| JP2656995B2 |
Attorney, Agent or Firm:
Hidesaku Yamamoto