Title:
DIAGNOSIS AND TREATMENT OF MALIGNANT NEOPLASM
Document Type and Number:
Japanese Patent JP2008285485
Kind Code:
A
Abstract:
To provide a method of diagnosing a malignant neoplasm in a mammal and a method of eliciting an immune response or conferring an immune response to a tumor cell (for example, a brain tumor) in a mammal.
The method of diagnosing and inhibiting the growth of a malignant neoplasm in a mammal comprises bringing a cell or a bodily fluid of the mammal into contact with an antibody which binds to a human aspartyl (asparaginyl)-hydroxylase (HAAH) polypeptide. A method of immunization to generate an HAAH-specific immune response is disclosed.
Inventors:
WANDS JACK R
DE LA MONTE SUZANNE
DEUTCH ALAN H
GHANBARI HOSSEIN A
DE LA MONTE SUZANNE
DEUTCH ALAN H
GHANBARI HOSSEIN A
Application Number:
JP2008126157A
Publication Date:
November 27, 2008
Filing Date:
May 13, 2008
Export Citation:
Assignee:
RHODE ISLAND HOSPITAL
International Classes:
C07K16/40; G01N33/543; A61K31/00; A61K31/4412; A61K31/45; A61K31/7088; A61K38/43; A61K39/00; A61K39/395; A61K45/00; A61K47/48; A61K48/00; A61K49/00; A61K49/16; A61K51/00; A61K51/10; A61P35/00; C07K14/47; C12N5/10; C12N9/02; C12N9/06; C12N15/02; C12N15/09; C12N15/113; C12P21/08; C12Q1/02; C12Q1/26; G01N33/53; G01N33/573; G01N33/574; G01N33/577
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi