Title:
がんの診断用バイオマーカー
Document Type and Number:
Japanese Patent JP7144037
Kind Code:
B2
Abstract:
To provide a diagnostic biomarker for cancer by which the presence of even early-stage cancer can be accurately determined.SOLUTION: When a methylation level of a specific cytosine in a double-stranded DNA fragment derived from RUNX3 gene in a blood serum sample or a blood plasma sample collected from a subject is higher than a methylation level in a subject who is not affected with cancer, it can be determined that the subject is highly possibly affected with cancer.SELECTED DRAWING: None
Inventors:
Hiroshi Suehiro
山▲崎▼ 隆弘
Tomomi Hoshida
山▲崎▼ 隆弘
Tomomi Hoshida
Application Number:
JP2018139564A
Publication Date:
September 29, 2022
Filing Date:
July 25, 2018
Export Citation:
Assignee:
Yamaguchi University
International Classes:
C12Q1/6886; C12Q1/6851; G01N33/50
Domestic Patent References:
| JP2004529619A | ||||
| JP2009247260A | ||||
| JP2014139139A |
Other References:
Oncology Reports,2007年,Vol. 18, No. 5,pp. 1225-1230
長浜由美, 他,ヒト食道,胃および大腸癌細胞株におけるRUNX3 mRNAスプライシングバリアントの発現.,日本癌学会学術総会記事,2005年,Vol. 64th,p. 458
Lung Cancer,2009年,Vol. 64, No. 1,pp. 92-97
長浜由美, 他,ヒト食道,胃および大腸癌細胞株におけるRUNX3 mRNAスプライシングバリアントの発現.,日本癌学会学術総会記事,2005年,Vol. 64th,p. 458
Lung Cancer,2009年,Vol. 64, No. 1,pp. 92-97
Attorney, Agent or Firm:
Hiroki Masaki
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Matsunashi Yasunori
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Matsunashi Yasunori
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Satoshi Morikawa
Hiroyuki Tomita