Title:
DIHYDROFOLATE REDUCTASE-ANTIALLERGIC PENTAPEPTIDE POLYMER FUSED PROTEIN (I)
Document Type and Number:
Japanese Patent JPH04117285
Kind Code:
A
Abstract:
NEW MATERIAL:A recombinant plasmid containing a base sequence encoding dihydrofolate reductase-antiallergic peptide polymer fused protein (I).
EXAMPLE: A recombinant plasmid wherein an antiallergic pentapeptide, a fused protein (I) of dimer contains an amino acid sequence shown by the formula (underline shows amino acid existing between dihydrofolate reductase and antiallergic pentapeptide).
USE: Production of DSDGK.
PREPARATION: A DNA encoding DSDGK polymer obtained by chemically synthesizing a single strand DNA and annealing both chains is inserted into a vector plasmid capable of manifesting DHFR.
Inventors:
BABA KENZO
IWAKURA MASAHIRO
OHASHI SHINICHI
TANAKA YOSHIO
IZUTSU HIROSHI
OBARA KAZUHIKO
TAKASUKA AKIKO
IWAKURA MASAHIRO
OHASHI SHINICHI
TANAKA YOSHIO
IZUTSU HIROSHI
OBARA KAZUHIKO
TAKASUKA AKIKO
Application Number:
JP12320290A
Publication Date:
April 17, 1992
Filing Date:
May 15, 1990
Export Citation:
Assignee:
AGENCY IND SCIENCE TECHN
HITACHI CHEMICAL CO LTD
HITACHI CHEMICAL CO LTD
International Classes:
C12N15/09; A61K38/00; A61K38/44; A61P37/08; C07K1/12; C07K1/22; C07K7/06; C07K14/00; C07K19/00; C12N1/21; C12N9/02; C12N15/12; C12N15/53; C12N15/62; C12P21/02; C12R1/19; (IPC1-7): A61K37/02; A61K37/50; C07K13/00; C12N1/21; C12N15/12; C12N15/53; C12N15/62; C12P21/02
Attorney, Agent or Firm:
Institute of Biotechnology, Industrial Technology Research Institute
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