Title:
Dimer type binding protein based on ornamentation ubiquitin
Document Type and Number:
Japanese Patent JP6146821
Kind Code:
B2
Abstract:
The present invention refers to novel dimeric proteins obtained from modified ubiquitin capable of binding targets with high affinity. The novel dimeric binding proteins comprise a combination of amino acid substitutions and at least one insertion of amino acids in one of the monomers. The invention is further directed to the use of said proteins in medical diagnosis or treatment methods.
Inventors:
Nerkomp, Joelk
Bosse-Donecke, Eiffa
Stuernagel, Arndt
Ulrich, Fiedler
Fiedler, Marx
Bosse-Donecke, Eiffa
Stuernagel, Arndt
Ulrich, Fiedler
Fiedler, Marx
Application Number:
JP2014515207A
Publication Date:
June 14, 2017
Filing Date:
June 15, 2012
Export Citation:
Assignee:
Navigo Proteins GmbH
International Classes:
C07K19/00; C12N15/09; C12P21/02
Domestic Patent References:
| JP2008500953A |
Attorney, Agent or Firm:
Patent business corporation Kita Aoyama International