Title:
疾病の判定および監視
Document Type and Number:
Japanese Patent JP4674317
Kind Code:
B2
Abstract:
The present invention relates to the diagnosis and monitoring of diseases and conditions by quantifying markers, including degradation products of disease-associated proteins, such as diketopiperazines composed of the two N-terminal amino acids or the two C-terminal amino acids of such proteins. The methods are useful for diagnosing or monitoring various diseases, including multiple sclerosis, Alzheimer's disease and ischemia. The invention further provides binding partners specific for the markers and compositions and kits for conducting the methods of the invention.
Inventors:
Bar-Oh, David
Bar-Oh, Rafael
Bar-Oh, Rafael
Application Number:
JP2005500360A
Publication Date:
April 20, 2011
Filing Date:
October 02, 2003
Export Citation:
Assignee:
DMI ACQUISITION CORP.
International Classes:
G01N33/68; A01N1/00; A01N1/02; A01N37/18; A61B1/00; A61K38/00; A61K39/395; C07K16/18; G01N33/00; G01N33/48; G01N33/483; G01N33/50; G01N33/53; G01N33/576; A61B
Domestic Patent References:
| JP2002527753A | ||||
| JP2002526764A | ||||
| JP2004518614A |
Foreign References:
| WO2002011676A1 | ||||
| WO2000020454A1 |
Other References:
小林功,入内島徳二,森昌朋,Neuropeptide Yとhistidyl-proline diketopiperazine,臨床検査,日本,1987年 9月,Vol.31,No.9,Page.984-991
Attorney, Agent or Firm:
Hironobu Onda
Makoto Onda
Atsushi Honda
Miho Ikegami
Makoto Onda
Atsushi Honda
Miho Ikegami