TREATMENT OF HEARING AND BALANCE IMPAIRMENTS WITH REDOX-ACTIVE THERAPEUTICS

Title:

TREATMENT OF HEARING AND BALANCE IMPAIRMENTS WITH REDOX-ACTIVE THERAPEUTICS

Document Type and Number:

Japanese Patent JP2017193590

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide a treatment of hearing and balance impairments with redox-active therapeutics.SOLUTION: According to the present invention, there is provided a composition and method for prophylactic or therapeutic treatment of a mammal for hearing or balance impairments involving neuronal damage, loss, or degeneration, by administration of a therapeutically effective amount of a redox-active therapeutic. There is also provided an improved composition and method for a treatment requiring administration of a pharmaceutical having an ototoxic side-effect in combination with a therapeutically effective amount of a redox-active therapeutic to treat the ototoxicity. In one embodiment, the invention relates to a method for treating a patient having or prone to having a hearing or balance impairment with a prophylactically or therapeutically effective amount of a redox-active therapeutic, to prevent, reduce or treat the incidence of, or severity of the hearing impairment.SELECTED DRAWING: None

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Inventors:

MILLER GUY M

Application Number:

JP2017151442A

Publication Date:

October 26, 2017

Filing Date:

August 04, 2017

Export Citation:

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Assignee:

BIOELECTRON TECH CORP

International Classes:

A61K45/00; A61K33/243; A61P1/08; A61P25/02; A61P27/16; A61P43/00

Domestic Patent References:

JPH08500091A	1996-01-09
JP2011509298A	2011-03-24

Foreign References:

WO2006130775A2	2006-12-07
WO2007035496A1	2007-03-29
WO2007100652A2	2007-09-07
US20070225261A1	2007-09-27

Other References:

ACTA OTO-LARYNGOLOGICA, vol. VOL.125, JPN6015051294, 2005, pages 510 - 512
NEUROREPORT, vol. 19, no. 3, JPN6015051296, February 2008 (2008-02-01), pages 277 - 281
MITOCHONDRION, vol. VOL.4, JPN6013037634, 2004, pages 675 - 694

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita

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