Title:
ドセタキセルの製造法
Document Type and Number:
Japanese Patent JP5113745
Kind Code:
B2
Abstract:
The present invention provides processes for the production of docetaxel. Docetaxel is produced by protecting the C(7) and the C(10) hydroxy groups of 10-DAB with a bridging silicon-based protecting group. The resulting 7,10-protected 10-DAB derivative is then derivatized and deprotected to form docetaxel.
Inventors:
Von Boo
Robert A. Holton
Robert A. Holton
Application Number:
JP2008515928A
Publication Date:
January 09, 2013
Filing Date:
June 08, 2006
Export Citation:
Assignee:
Florida State University Research Foundation, Inc.
International Classes:
C07D305/14; C07F7/18; A61K31/337; A61P35/00
Domestic Patent References:
| JP2000500437A | ||||
| JP8506339A | ||||
| JP3086860A |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Yasuo Shibata
Kenichi Morizumi
Takuji Yamada
Yasuo Shibata
Kenichi Morizumi