Title:
DOPAMINE-BETA-HYDROXYLASE INHIBITOR
Document Type and Number:
Japanese Patent JPS62283967
Kind Code:
A
Abstract:
Compounds of Formula : in which n is 0 to 5, R is hydrogen or C1-4alkyl and X is hydrogen, halo, C1-4alkyl, CN, NO2, SO2NH2, COOH, CHO, OH, CH2OH, C1-4alkoxy, CF3, SO2CH3, SO2CF3 or CO2CaH2a+1 wherein a is 1 to 5 or any synthetically accessible combination thereof of up to 5 substituents or any pharmaceutically acceptable salt or hydrate thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine beta -hydroxylase inhibitors.
Inventors:
JIYOSEFU ARAN FUINKERUSUTAIN
ROURENSU AIBAN KURUSU
ROURENSU AIBAN KURUSU
Application Number:
JP12358587A
Publication Date:
December 09, 1987
Filing Date:
May 20, 1987
Export Citation:
Assignee:
SMITHKLINE BECKMAN CORP
International Classes:
A61K31/41; A61P1/04; A61P7/10; A61P9/04; A61P9/08; A61P9/12; A61P43/00; C07C67/00; C07C239/00; C07C281/02; C07C301/00; C07C303/40; C07C311/37; C07C313/00; C07C315/04; C07C317/32; C07C325/00; C07C337/06; C07D249/12; (IPC1-7): A61K31/41; C07C133/00; C07C143/80; C07C147/12; C07C159/00; C07D249/12
Attorney, Agent or Firm:
Aoyama Aoi
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