Title:
薬物依存症治療薬
Document Type and Number:
Japanese Patent JP4359711
Kind Code:
B2
Abstract:
Remedies for drug addiction which contain as the active ingredient k-opioid receptor agonists typified by the compounds represented by general formula (I). These k-opioid receptor agonists are useful as remedies for drug addiction which are reduced in side effects and act on the reward effect expression mechanism so as to inhibit the expression of mental addiction and physical addiction simultaneously, different from the symptomatic therapy conventionally employed in treating drug addiction.
Inventors:
Hiroshi Nagase
Endo Takashi
Tsutomu Suzuki
Kuniaki Kawamura
Koji Oshima
Inada Hideo
Endo Takashi
Tsutomu Suzuki
Kuniaki Kawamura
Koji Oshima
Inada Hideo
Application Number:
JP51597799A
Publication Date:
November 04, 2009
Filing Date:
September 02, 1998
Export Citation:
Assignee:
TORAY INDUSTRIES,INC.
International Classes:
A61K31/485; A61P25/32; A61P25/34; A61P25/36; C07D489/08; C07D489/00
Domestic Patent References:
| JP61063658A | ||||
| JP61271275A | ||||
| JP5507291A |
Foreign References:
| WO1997015294A1 | ||||
| WO1997015081A1 |
Other References:
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EUROPEAN JOURNAL OF PHARMACOLOGY, 1997年 3月, Vol. 321, No. 3, pp. 265-271
THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1996年 , Vol. 276, No. 2, 545-554
NEUROSCIENCE LETTERS, 1994年, Vol. 181, No. 1-2, pp. 57-60
BRAIN RESEARCH, 1993年, Vol. 616, No. 1-2, pp. 335-8
FOLIA PHARMACOLOGICA JAPONICA, 1997年 4月, Vol. 109, No. 4, pages 165-173
NEUROPHARMACOLOGY, 1993年, Vol. 32, No. 12, pp. 1315-1323
MOLECULAR MEDICINE, 1995年, Vol. 32, No. 2, pp. 140-145
PROC. NATL. ACAD. SCI. USA, 1988年, Vol. 85, No. 12, pp.5274-5278