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Title:
DRUG COMPOSITION
Document Type and Number:
Japanese Patent JPS63246364
Kind Code:
A
Abstract:
Compounds of the following formula have pharmaceutical properties: in which X is R min (HO)C=C(CN)-, R<1>(CO)-CH(CN)- or R<1> and R<2> are each hydrogen or C1-6 alkyl, R<3>, R<4>, R<5> and R<6> are each hydrogen, hydroxy, halogen, nitro, cyano, carboxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halo-substituted C1-4 alkyl, halo-substituted C1-4 alkoxy, halo substituted C1-4 alkythio, C2-5 alkoxycarbonyl, optionally substituted phenyl, optionally substituted phenoxy, R min R sec N- where R min and R sec are each hydrogen or C1-4 alkyl or R'''CONH- where R''' is C1-4 alkyl, or a group of the formula -CR<7>R<8>R<9> in which R<7>,R<8> and R<9> are each C1-6 alkyl, halo-substituted C1-6 alkyl or optionally substituted phenyl, or R<7> and R<8>, together with the carbon atom to which they are attached, form a cycloalkyl group containing 3 to 7 carbon atoms, or R<7>, R<8> and R<9> together with the carbon atom to which they are attached, form a bicycloalkyl group containing 4 to 9 carbon atoms, and Y is a 5- or 6-membered heterocyclic ring excluding pyrazole; and salts thereof.

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Inventors:
PIITAA SAADEIASU GARAGAA
TERANSU AREN HITSUKUSU
Application Number:
JP19800787A
Publication Date:
October 13, 1988
Filing Date:
August 07, 1987
Export Citation:
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Assignee:
LILLY INDUSTRIES LTD
International Classes:
A61K31/34; A61K31/341; A61K31/38; A61K31/381; A61K31/395; A61K31/40; A61K31/415; A61K31/42; A61K31/421; A61K31/425; A61K31/426; A61K31/44; A61K31/496; A61K31/505; A61P29/00; A61P37/00; C07D207/335; C07D207/34; C07D213/75; C07D239/42; C07D233/88; C07D263/48; C07D275/02; C07D277/20; C07D277/46; C07D307/66; C07D333/36; C07D413/12; C07D417/12; C07D521/00; (IPC1-7): A61K31/34; A61K31/38; A61K31/395; A61K31/40; A61K31/415; A61K31/42; A61K31/425; A61K31/44; A61K31/505; C07D207/335; C07D213/75; C07D233/88; C07D239/42; C07D263/48; C07D275/02; C07D277/46; C07D307/66; C07D333/36; C07D417/12; C07D521/00
Domestic Patent References:
JPS5371070A1978-06-24
Attorney, Agent or Firm:
Minoru Nakamura



 
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