DRUG COMPOUND - LILLY INDUSTRIES LTD

Title:

DRUG COMPOUND

Document Type and Number:

Japanese Patent JPS63239259

Kind Code:

A

Abstract:

N-aryl-amide cpds. of the formula (I) and their salts are new. X is R1(OH)C=C(CN)-, R1(CO)-CH(CN)- or gp. (i); R1 and R2 are each H or 1-6C alkyl; R3,R4 and R5 are each H, OH, halogen, NO2, CN, CO2H, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, 1-4C haloalkyl, 1-4C haloalkoxy, 1-4C haloalkylthio, 2-5C alkoxycarbonyl, opt. substd. phenyl, opt. substd. phenoxy, NR'R'' or NHCOR''' (R' and R'' are each H or 1-4C alkyl and R''' is 1-4C alkyl); R6,R7 and R8 are each 1-6C alkyl, 1-6C haloalkyl or opt. substd. phenyl, or R6 and R7 together with the adjacent C atom form a 3-7C cycloalkyl gp., or R6, R7 and R8 together with the adjacent C atom form or 4-9C bicycloalkyl gp..

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Inventors:

PIITAA SAADEIASU GARAGAA
TERANSU AREN HITSUKUSU
GUREIAMU UORUTAA MARIA

Application Number:

JP19800687A

Publication Date:

October 05, 1988

Filing Date:

August 07, 1987

Export Citation:

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Assignee:

LILLY INDUSTRIES LTD

International Classes:

A61K31/16; A61K31/275; A61K31/33; A61K31/41; C07D261/18; A61K31/42; A61P17/00; A61P29/00; A61P37/06; C07C67/00; C07C253/00; C07C253/30; C07C255/23; C07C255/27; C07C255/42; C07D261/06; C07D261/16; (IPC1-7): A61K31/275; A61K31/42; C07C121/80; C07D261/18

Attorney, Agent or Firm:

Minoru Nakamura

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