To provide a drug sustained release agent having a high strength, capable of sustainedly releasing a wide range of drugs over a long period and having excellent bone conductivity.
This drug sustained release agent is obtained by mixing calcium phosphate ceramic porous granules having a film of a first biodegradable organic material on the surface with particles of a second biodegradable organic material containing the drug and pressure molding the resultant mixture. Furthermore, the drug sustained release agent comprises the calcium phosphate ceramic porous granules containing the first drug, a biodegradable organic material layer formed by coating the surface of the porous granules therewith and a calcium phosphate ceramic layer formed by coating the surface of the biodegradable organic material layer and containing the second drug.
IRIE HIROYUKI
MATSUOKA NAOYUKI
HAKAMAZUKA KOJI
NAKAMURA TAKEAKI
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