Title:
CCRL2の活性を調節する薬剤及びそれを使用する方法
Document Type and Number:
Japanese Patent JP4734256
Kind Code:
B2
Abstract:
A method of detecting an agent that modulates the activity of CCRL2, the method comprising: (a) contacting a CCRL2 polypeptide with a macrophage inflammatory protein-4 (MIP-4) polypeptide in the presence of a candidate agent under conditions, which in the absence of the test agent, permit the binding of the MIP-4 polypeptide to the CCRL2 polypeptide; and (b) determining whether the candidate agent is capable of modulating the interaction between said CCRL2 polypeptide and said MIP-4 polypeptide.
Inventors:
Tinsley, Jonason, Mark
Application Number:
JP2006542005A
Publication Date:
July 27, 2011
Filing Date:
December 02, 2004
Export Citation:
Assignee:
Oxagen Limited
International Classes:
C12N15/09; C12Q1/02; C12Q1/34; C12Q1/48; C12Q1/68; C12Q1/70; G01N33/68; C07K16/28; G01N33/15
Other References:
The Journal of biological chemistry. 2002, Vol.277, No.27, p.24584-24593
European journal of immunology. 2001, Vol.31, No.12, p.3755-3762
European journal of immunology. 2002, Vol.32, No.2, p.494-501
Science. 1999, Vol.286, No.5439, p.525-528
European journal of immunology. 2001, Vol.31, No.12, p.3755-3762
European journal of immunology. 2002, Vol.32, No.2, p.494-501
Science. 1999, Vol.286, No.5439, p.525-528
Attorney, Agent or Firm:
Takashima Ichi