Title:
色素カップリングマンノシル血清アルブミン複合体およびこれを含むリンパ節プロービング組成物
Document Type and Number:
Japanese Patent JP6748789
Kind Code:
B2
Abstract:
The present invention relates to a pigment-coupled mannosyl serum albumin complex and a lymph node-probing composition comprising the same. More particularly, when administered to mice, a pigment-coupled mannosyl serum albumin complex can be observed with the naked eye to exist in a condense state for a long period of time in the inguinal lymph node. Thus, the complex and a composition comprising the same can be useful for probing lymph nodes.
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Inventors:
Jeong
Lee, Yun-Sun
Lee, Jiyoung
Lee, Yun-Sun
Lee, Jiyoung
Application Number:
JP2019551334A
Publication Date:
September 02, 2020
Filing Date:
March 16, 2018
Export Citation:
Assignee:
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
International Classes:
A61K49/00; A61K51/08; C07K14/765
Domestic Patent References:
| JP2005226021A |
Foreign References:
| US20160045621 |
Other References:
三輪 晃一 ほか,胃癌センチネルリンパ節生検の手技,外科治療,2000年 9月,第83巻,第3号,p.292-298
Oh Y et al.,Thoracoscopic Color and Fluorescence Imaging System for Sentinel Lymph Node Mapping in Porcine Lung Using Indocyanine Green-Neomannosyl Human Serum Albumin: Intraoperative Image-Guided Sentinel Nodes Navigation,Annals of Surgical Oncology,2014年,Vol.21, No.4,p.1182-1188,DOI: 10.1245/s10434-013-3381-z
Tsopelas C et al.,99mTc-Evans Blue Dye for Mapping Contiguous Lymph Node Sequences and Discriminating the Sentinel Lymph Node in an Ovine Model,Annals of Surgical Oncology,2006年,Vol.13, No.5,p.692-700,DOI: 10.1245/ASO.2006.04.020
Oh Y et al.,Thoracoscopic Color and Fluorescence Imaging System for Sentinel Lymph Node Mapping in Porcine Lung Using Indocyanine Green-Neomannosyl Human Serum Albumin: Intraoperative Image-Guided Sentinel Nodes Navigation,Annals of Surgical Oncology,2014年,Vol.21, No.4,p.1182-1188,DOI: 10.1245/s10434-013-3381-z
Tsopelas C et al.,99mTc-Evans Blue Dye for Mapping Contiguous Lymph Node Sequences and Discriminating the Sentinel Lymph Node in an Ovine Model,Annals of Surgical Oncology,2006年,Vol.13, No.5,p.692-700,DOI: 10.1245/ASO.2006.04.020
Attorney, Agent or Firm:
Kiyoji Kuzuwa