Title:
EBNA1 INHIBITORS AND THEIR METHODS OF USE
Document Type and Number:
Japanese Patent JP2020196723
Kind Code:
A
Abstract:
To provide compositions and methods useful for treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis.SOLUTION: Pharmaceutical compositions comprise EBNA1 inhibitors useful for treatment of diseases caused by EBNA1 activity. The pharmaceutical compositions also comprise EBNA1 inhibitors useful for treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. The pharmaceutical compositions also comprise EBNA1 inhibitors useful for treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection.SELECTED DRAWING: None
Inventors:
TROY E MESSICK
GARRY R SMITH
ALLEN B REITZ
PAUL M LIEBERMAN
MARK E MCDONNELL
CHUNG YOUNG
VENKATA VELVADAPU
GARRY R SMITH
ALLEN B REITZ
PAUL M LIEBERMAN
MARK E MCDONNELL
CHUNG YOUNG
VENKATA VELVADAPU
Application Number:
JP2020129107A
Publication Date:
December 10, 2020
Filing Date:
July 30, 2020
Export Citation:
Assignee:
WISTAR INST OF ANATOMY AND BIOLOGY THE
International Classes:
C07D207/327; A61K31/192; A61K31/196; A61K31/343; A61K31/36; A61K31/381; A61K31/40; A61K31/402; A61K31/404; A61K31/41; A61K31/415; A61K31/4155; A61K31/416; A61K31/417; A61K31/4174; A61K31/4178; A61K31/4184; A61K31/4192; A61K31/4196; A61K31/42; A61K31/426; A61K31/427; A61K31/428; A61K31/437; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4427; A61K31/4439; A61K31/47; A61K31/4709; A61K31/495; A61K31/4985; A61K31/505; A61K31/5377; A61K31/538; A61K31/541; C07C63/66; C07C63/74; C07C65/19; C07C65/28; C07C69/76; C07C229/38; C07C229/56; C07C229/64; C07C235/00; C07C311/17; C07C317/44; C07D207/08; C07D207/12; C07D207/14; C07D207/16; C07D207/333; C07D209/18; C07D209/30; C07D209/42; C07D213/55; C07D213/74; C07D215/14; C07D217/16; C07D231/12; C07D231/56; C07D233/61; C07D235/04; C07D239/24; C07D239/42; C07D249/06; C07D257/04; C07D261/08; C07D265/36; C07D277/30; C07D295/033; C07D295/155; C07D295/192; C07D307/80; C07D317/60; C07D333/60; C07D401/04; C07D401/10; C07D401/12; C07D403/10; C07D403/12; C07D405/12; C07D409/10; C07D409/12; C07D413/10; C07D417/10; C07D471/04; C07D487/04
Domestic Patent References:
| JP2008505125A | 2008-02-21 | |||
| JP6744218B2 | 2020-08-19 |
Foreign References:
| CN1634810A | 2005-07-06 | |||
| WO2007002433A1 | 2007-01-04 | |||
| WO2011090911A1 | 2011-07-28 | |||
| WO2010100475A1 | 2010-09-10 |
Other References:
DATABASE REGISTRY (STN) RN 1259291-73-0,[ONLINE], JPN6021034662, 13 January 2011 (2011-01-13), ISSN: 0004586744
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto