Title:
アクリダン化合物からの電気化学ルミネセンス
Document Type and Number:
Japanese Patent JP4733334
Kind Code:
B2
Abstract:
Methods are disclosed for producing electrochemiluminescence by electrochemically oxidizing an acridan compound at an electrode in the presence of a peroxide. Maintaining a sufficiently positive potential results in continuous oxidation of the acridan compound to an acridinium compound which reacts with peroxide to produce the luminescence. Light emission can be reversibly and repeatedly cycled on and off by sweeping the potential between two values. The acridan compounds can be provided with a labeling group for linking to an analyte or analyte binding partner. The present electrochemiluminescent reaction can find use in assay methods for detecting analytes by immunoassays and nucleic acid assays.
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Inventors:
Hashem Akhavan-Tufte
Robert Wilson
David Jog Sifferin
Robert Wilson
David Jog Sifferin
Application Number:
JP2002505848A
Publication Date:
July 27, 2011
Filing Date:
June 26, 2001
Export Citation:
Assignee:
Lumigen Incorporated
International Classes:
G01N21/66; G01N21/76; C07D219/04; C12Q1/68; C12Q1/6816; G01N33/532; G01N33/533
Domestic Patent References:
| JP9509938A | ||||
| JP9512041A | ||||
| JP3505373A | ||||
| JP2001516760A |
Attorney, Agent or Firm:
Ichiro Honda
Keiko Honda
Keiko Honda