ENCAPSULATED POLYNUCLEOTIDES AND METHODS OF USE

Title:

ENCAPSULATED POLYNUCLEOTIDES AND METHODS OF USE

Document Type and Number:

Japanese Patent JP2023165916

Kind Code:

A

Abstract:

To provide encapsulated polynucleotides and methods of use.SOLUTION: The present disclosure relates to polynucleotides comprising a nucleic acid sequence encoding a replication competent viral genome, where the polynucleotide is capable of producing a replication competent virus when introduced into a cell by a non-viral delivery vehicle. The present disclosure further relates to the encapsulation of the polynucleotides and the use of the polynucleotides and/or particles for the treatment and prevention of cancer.SELECTED DRAWING: Figure 1

Inventors:

MITCHELL H FINER
EDWARD KENNEDY
LORENA LERNER

Application Number:

JP2023166265A

Publication Date:

November 17, 2023

Filing Date:

September 27, 2023

Export Citation:

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Assignee:

ONCORUS INC

International Classes:

A61K9/16; C12N15/86; A61K31/7088; A61K31/7105; A61K31/711; A61K35/76; A61K35/763; A61K35/768; A61K39/395; A61K47/02; A61K47/04; A61K47/18; A61K47/24; A61K47/28; A61K47/36; A61K48/00; A61P1/16; A61P11/00; A61P35/00; C12N15/113; C12N15/33; C12N15/88

Attorney, Agent or Firm:

Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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