Title:
治療薬のカプセル化方法、およびその使用
Document Type and Number:
Japanese Patent JP2014509617
Kind Code:
A
Abstract:
The current invention relates to encapsulation methods comprising alginate-based microencapsulation for the immune-protection and long-term functioning of biological material or therapeutics. The biological material or the therapeutics are encompassed by a membrane formed by jellifying an alginate polymer. Specifically, although by no means exclusively, the encapsulation system is intended for use in allo-or xenotransplantation. The membrane provides for a protective barrier of the encapsulated material, ensuring the longevity and preventing unwanted influences from outside the barrier, such as inflammatory reactions or immune-responses. The invention is furthermore directed to methods of producing and providing the encapsulated products for use in cell therapies. The therapeutic products obtained by the encapsulation method may provide a method for ameliorating of treating a range of conditions.
Inventors:
Bowmans, Miriam Lee Willie
Shonyans, Luk
Shuek-Break, Gudmund
Shonyans, Luk
Shuek-Break, Gudmund
Application Number:
JP2014501513A
Publication Date:
April 21, 2014
Filing Date:
March 07, 2012
Export Citation:
Assignee:
BETA-CELL NV
International Classes:
A61K9/50; A61K31/7105; A61K31/711; A61K35/12; A61K35/28; A61K35/30; A61K35/32; A61K35/39; A61K35/407; A61K38/00; A61K38/22; A61K39/00; A61K39/395; A61K47/02; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61L27/00; A61P3/10
Attorney, Agent or Firm:
Keiichiro Saikyo