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Title:
ENDOTHELIN ANTAGONIST
Document Type and Number:
Japanese Patent JPH107574
Kind Code:
A
Abstract:

To obtain an endothelin antagonist for eye drop containing 15 keto- prostaglandin F compound as an active ingredient and useful for treating various diseases and morbid state in which endothelin participates.

This endothelin antagonist contains 15-keto-prostaglandin F compound (except a compound having ≥8 α-chain skeleton carbon atoms) such as a 13,14-dihydro-15-keto-prostaglandin F compound or 13,14-dihydro-15-keto-20- ethyl prostaglandin F compound as an active ingredient and is effective in treating diabetic retinopathy, retinopathia renalis, occlusion of retinal vein, etc.


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Inventors:
SUGIYAMA TETSUYA
AZUMA IKUO
UENO TAKASHI
Application Number:
JP15538396A
Publication Date:
January 13, 1998
Filing Date:
June 17, 1996
Export Citation:
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Assignee:
R TECH UENO KK
International Classes:
A61K9/08; A61K31/557; A61K31/5575; A61P27/02; A61P43/00; C07C405/00; (IPC1-7): A61K31/557; A61K9/08
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)



 
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