Title:
内毒素結合性リガンドおよびそれらの使用
Document Type and Number:
Japanese Patent JP2005525874
Kind Code:
A
Abstract:
An affinity ligand-matrix conjugate of the structure Z-Spacer-[NX-A]m-NY-A-NK2 is useful for the isolation, separation, purification, characterization, identification or quantification of endotoxins in an aqueous system, wherein m is an integer of at least one; each A independently represents an optionally substituted linear, branched or cyclic saturated hydrocarbon chain containing 1 to 6 carbon atoms; each X independently represents hydrogen or alkyl; Y is X or A-NX2; and Z is a support matrix attached to the ligand through an optional spacer arm (Spacer).
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Inventors:
Steven James Burton
Thaddeus Podgowski
Saji S. Epen
Thaddeus Podgowski
Saji S. Epen
Application Number:
JP2004505107A
Publication Date:
September 02, 2005
Filing Date:
May 22, 2003
Export Citation:
Assignee:
ProMetic BioSciences Ltd
International Classes:
A61M1/16; A61L2/00; A61M1/34; A61M1/36; B01D67/00; B01J20/22; B01J20/32; B01D15/38; (IPC1-7): A61M1/16; A61M1/34; A61M1/36; B01J20/22
Attorney, Agent or Firm:
Mitsuo Tanaka
Michiko Matsutani
Tadayuki Motoyama
Kenji Tomita
Mina Shiga
Michiko Matsutani
Tadayuki Motoyama
Kenji Tomita
Mina Shiga