To provide an enzyme composition for decreasing glucose in the stomach and/or the intestines and reducing calorie uptake by its intake and utilization of enzyme reaction and for converting glucose into gluconic acid.

This enzyme composition includes at least a redox enzyme selected from the group consisting of flavin adenine dinucleotide-bound glucose dehydrogenase enzyme, glucose oxidase, NAD(P) dependent glucose dehydrogenase enzyme and pyrroloquinoline quinone dependent glucose dehydrogenase enzyme and decreases glucose in the stomach and/or the intestines by intake. Digestive exogenous enzyme containing the enzyme composition, supplement and material of healthy foods are also included in this patent.