Title:
細胞外標的化薬物複合体
Document Type and Number:
Japanese Patent JP2013504585
Kind Code:
A
Abstract:
The present invention relates to, inter alia, extracellular drug conjugates (EDC) in which an antibody or other targeting agent (e.g. a targeting moiety) is linked to a drug through a linker (e.g. a non-cleavable linker). These conjugates are useful in the treatment of disease and/or as a tool in the evaluation of biological systems.
Inventors:
Prudent, James Earl.
Thoson, John S.
Boletieri, Jill Hutchinson
Hutchinson, Charles Earl
Thoson, John S.
Boletieri, Jill Hutchinson
Hutchinson, Charles Earl
Application Number:
JP2012528898A
Publication Date:
February 07, 2013
Filing Date:
September 09, 2010
Export Citation:
Assignee:
St. Rose, LRC
International Classes:
A61K39/395; A61K31/58; A61K31/704; A61K45/00; A61K47/34; A61K47/48; A61P3/12; A61P9/00; A61P9/10; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
| JP2007520450A | 2007-07-26 | |||
| JP2005517032A | 2005-06-09 | |||
| JPH08504284A | 1996-05-07 | |||
| JP2011523628A | 2011-08-18 |
Foreign References:
| WO2008121797A1 | 2008-10-09 |
Attorney, Agent or Firm:
Takeshi Oshio