Title:
リポペプチド抗生物質の抽出的精製
Document Type and Number:
Japanese Patent JP4223810
Kind Code:
B2
Abstract:
The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics, such as those having a cyclic peptide or cyclic depsipeptide core, in high yield and purity. In particular, there is provided a method of extracting a variety of acidic lipopeptide antibiotics, directly or indirectly, into water immiscible organic solvents by using a divalent cation chelation procedure.
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Inventors:
Borders, Donald Bee.
Francis, Noreen Dee.
Fantini, Amedeo Ae.
Francis, Noreen Dee.
Fantini, Amedeo Ae.
Application Number:
JP2002556605A
Publication Date:
February 12, 2009
Filing Date:
January 10, 2002
Export Citation:
Assignee:
Mygenics Incorporated
International Classes:
C07K1/14; C12P1/04; A01N37/46; B01D11/04; C07K7/08; C07K7/56; C07K9/00; C07K11/02; A61K38/00
Domestic Patent References:
| JP7097394A | ||||
| JP2004528268A |
Other References:
Biochim. Biophys. Acta, vol. 985, pp.60-66 (1989)
Biochem. Biophys. Res. Commun., vol. 150, pp. 384-390 (1988)
Biochem. Biophys. Res. Commun., vol. 150, pp. 384-390 (1988)
Attorney, Agent or Firm:
Hidesaku Yamamoto
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