[F-18]-LABELED L-GLUTAMIC ACID, [F-18]-LABELED L-GLUTAMINE, DERIVATIVE THEREOF, AND USE AND METHOD THEREOF FOR PREPARATION THEREOF

Title:

[F-18]-LABELED L-GLUTAMIC ACID, [F-18]-LABELED L-GLUTAMINE, DERIVATIVE THEREOF, AND USE AND METHOD THEREOF FOR PREPARATION THEREOF

Document Type and Number:

Japanese Patent JP2014088389

Kind Code:

A

Abstract:

To provide a diagnostic agent for positron emission tomography, comprising a [F-18]-labeled compound.

A diagnostic agent for positron emission tomography (PET) comprises a compound which is a L-glutamic acid or L-glutamic acid derivative labeled with F-18, represented by the formula (I). [In the formula, A represents hydroxyl, NH2 or O-Z; G represents hydroxyl or O-Z, R¹ and R² represent hydrogen or ¹⁸F, where any one of the substituents R¹ or R² is ¹⁸F isotope and the other substituent is hydrogen; and Z represents a metal cation.]

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Inventors:

LUDGER DINKELBORG
FRIEBE MATTHIAS
KRASIKOWA RAISA NIKOLAEVNA
YURI BELOKON
KUZNETSOVA OLGA FEDOROVNA
KEITH GRAHAM
LEHMANN LUTZ
MATHIAS BERNDT
HERIBERT SCHMITT-WILLICH

Application Number:

JP2013249418A

Publication Date:

May 15, 2014

Filing Date:

December 02, 2013

Export Citation:

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Assignee:

PIRAMAL IMAGING SA
AN NESMEYANOV INST OF ORGANOELEMENT COMPOUNDS THE RUSSIAN ACADAMY OF SCIENCES INEOS RAS
NP VETUTELLEVA INST OF THE HUMAN BRAIN OF THE RUSSIAN ACADEMY OF SCIENCES IHB RAS

International Classes:

C07B57/00; A61K51/00; C07B59/00; C07C229/24; C07C237/06; C07F15/04

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe

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