Title:
ＦＯＸＭ１由来ペプチドおよびそれを含むワクチン
Document Type and Number:
Japanese Patent JP7142276
Kind Code:
B2
Abstract:
The present invention provides FOXM1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
Inventors:
Sachiko Yamashita
Tetsuro Hikichi
Tetsuro Hikichi
Application Number:
JP2021067420A
Publication Date:
September 27, 2022
Filing Date:
April 13, 2021
Export Citation:
Assignee:
OncoTherapy Science Co., Ltd.
International Classes:
C12N15/12; A61K9/107; A61K35/12; A61K35/15; A61K35/17; A61K38/08; A61K39/00; A61K48/00; A61P35/00; A61P35/02; A61P37/04; C07K7/06; C07K7/08; C07K16/18; C12N5/0783; C12N5/0784; C12Q1/02
Domestic Patent References:
| JP2012517799A |
Foreign References:
| WO2014036562A2 | ||||
| WO2009025196A1 |
Attorney, Agent or Firm:
Masao Haruna
Shimizu Hatsushi
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Shimizu Hatsushi
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto