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Title:
COMPOSITION FOR ORAL CAVITY
Document Type and Number:
Japanese Patent JP3241923
Kind Code:
B2
Abstract:

PURPOSE: To obtain a composition for oral cavity having an excellent effect of treatment or prophylaxis of periodontal diseases, and a good taste and feeling, by containing salt, sodium bicarbonate and an antiphlogistic agent.
CONSTITUTION: This composition contains a slat particles with an average particle diameter of 150-450μm, a sodium bicarbonate particles with an average particle diameter of 45-450μm, and one or more kind of antiphlogistic agent selected from a group consisting of alantoin and its salts, epidihydrocholesterol, dihydrocholesterol, lysozyme hydrochloride, an ascorbic acid derivative and their salts, azlene, matricaria, lingstium, and enidium as effective components. Their contents are 10wt.% or more of salt, with a combining ratio of salt and sodium bicarbonate of 1/0.5-1/3 in wt. ratio, and 0.001-0.2wt.% of the antiphlogistic agent. This composition can be used as a tooth paste by combining a water soluble polishing agent and as an ointment suitably for gingiva by combining an oil component or a water soluble high polymer. This composition is capable of keeping an effective concentration of the antiphlogistic agent at a high level, without causing an unpleasant salty taste of the salt and without combining a high concentration of the antiphlogistic agent.


Inventors:
Ryozo Nakai
Koji Maeda
Hidenori Yoshida
Taiki Eguchi
Application Number:
JP4945894A
Publication Date:
December 25, 2001
Filing Date:
March 18, 1994
Export Citation:
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Assignee:
Kao Corporation
International Classes:
A61K8/00; A61K8/20; A61K8/25; A61K8/26; A61K8/40; A61K8/49; A61K8/92; A61K8/96; A61K8/97; A61Q11/00; (IPC1-7): A61K7/16
Domestic Patent References:
JP5033691A
JP62155207A
JP6335515A
JP558865A
JP672834A
JP8506098A
Attorney, Agent or Firm:
Osamu Hatori