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Title:
第VIII因子キメラおよびハイブリッドポリペプチドならびにその使用法
Document Type and Number:
Japanese Patent JP7273487
Kind Code:
B2
Abstract:
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.

Inventors:
Jennifer A. Dumont
Susan Low
Alan Jay Bitonty
Glen Pierce
Alvin look
Hey Yang Jean
Byron McKinney
Matt Ottomar
Jarg Somer
Karen Newgent
lee lian
Robert Peters
Application Number:
JP2018223631A
Publication Date:
May 15, 2023
Filing Date:
November 29, 2018
Export Citation:
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Assignee:
Bioverativ Therapeutics Incorporated
International Classes:
A61K38/37; A61K47/54; A61K47/64; A61K47/68; A61P7/04; A61P43/00
Foreign References:
WO2011069164A2
Other References:
Biochem J., 1995, vol.312, p.49-55
The Journal Of Biological Chemistry, 1994, vol.269, No.25, p.17329-17337
日本輸血学会雑誌, 1990, Vol.36, No.3, p.406-410
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto