Title:
ＲＯＣＫの阻害剤としての５員および二環式のヘテロ環アミド
Document Type and Number:
Japanese Patent JP7206252
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I):or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.
Inventors:
Peter W. Grants
Vladimir Radiata
Indawati Delkka
George O Tora
Tarn Kumar Myshall
Lagram Tangirara
Kamalajji Tiyagalajan
Vladimir Radiata
Indawati Delkka
George O Tora
Tarn Kumar Myshall
Lagram Tangirara
Kamalajji Tiyagalajan
Application Number:
JP2020501316A
Publication Date:
January 17, 2023
Filing Date:
July 11, 2018
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D231/14; A61K31/427; A61K31/437; A61K31/497; A61K31/5377; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P21/00; A61P25/00; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D401/14; C07D403/12; C07D417/12; C07D417/14; C07D471/04; C07D491/052; C07D495/04; C07D519/00
Foreign References:
| WO2016010950A1 | ||||
| WO2007142323A1 |
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Futami Kamahira
Masahiro Suwon
Shinagawa
Futami Kamahira
Masahiro Suwon