PURPOSE: To obtain a 5-membered heterocyclic compound having useful pharmacological properties, e.g. aggregation inhibitory action.
CONSTITUTION: The compound of formula [one of X1 to X5 is A-B-C-N <, A-B-C-CH<, A-B-C-C(<)-, second group is RbO-CO-E-D-N<, RbO-CO-E-D-CH< or RbO-CO-E-D-C(<)-, third group is S, HN, R6N, (R7)2C or the like; fourth group is O, S, N or the like; fifth group is N, (R7)2C or the like; A is substitutable cycloalkyl or substitutable phenyl; B is bond, alkylene, OCH2, SCH2 or the like; C is phenylene, piridinylene, 1,4-cyclohexylene or the like; D is alkylene, phenylene, cycloalkylene or the like; E is bond, alkylene or the like; R' is H, alkyl, cycloalkyl or the like; R6 is alkyl, phenyl or the like; R7 is H, alkyl or the like], e.g. 2-(trans-4-carboxy-cyclohexyl)-5-[4-(4-piperidinyl)- phenyl]-1,3,4-thiadiazole.
FURANKU HINMERUSUBATSUHA
FUORUKUHARUTO AUSHIYUTERU
HERUMUUTO PIIPERU
TOOMASU MIYUURAA
YOHANESU BUAIZENBERUGAA
BURIAN GUUTO
