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Title:
複数種類のタンパク質を高スループットで産生および精製するための、融通性の高い方法および装置
Document Type and Number:
Japanese Patent JP2005511755
Kind Code:
A
Abstract:
A plurality of proteins of interest, or peptides of interest, or other genetically expressed materials, are screened and subsequently produced using any of a variety of expression systems. The plurality of proteins are extracted from a plurality of separate, processed green juices, each green juice containing one of the proteins of interest. A multi-channel apparatus processes the various green juices, one green juice per channel. The apparatus is computer controlled such that the various valves in each channel and pump are controlled in an automated manner to extract each protein of interest and deliver each protein of interest into its own storage vessel.

Inventors:
Smith, Mark, Elle.
Palmer, Kennis
Pogue, Gregory, Pee.
Limbo, John, A.
Hanley, Kathryn, M.
Manion, David, Pea.
Wolf, Jersion, M.
Application Number:
JP2003551542A
Publication Date:
April 28, 2005
Filing Date:
December 04, 2002
Export Citation:
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Assignee:
Large Scale Biology Corporation
International Classes:
C12N15/09; C07K1/22; C07K5/078; C07K14/47; C12M1/00; A61K38/00; B01D15/18; B01D15/38; (IPC1-7): C07K1/22; C12N15/09
Domestic Patent References:
JPH06166698A1994-06-14
JPS63251095A1988-10-18
JPH06505624A1994-06-30
Foreign References:
WO1999046288A21999-09-16
Other References:
PROTEIN EXPRESSION AND PURIFICATION, vol. 15, JPN6008011253, 1999, pages 34 - 39, ISSN: 0000996202
PROTEIN EXPRESSION AND PURIFICATION, vol. 22, JPN6008011255, 2001, pages 359 - 366, ISSN: 0000996203
GENOME RES., vol. 11, JPN6008011257, September 2001 (2001-09-01), pages 1730 - 1735, ISSN: 0000996204
新村出編, 広辞苑, vol. 第五版, JPN6008011258, 1998, pages 2709, ISSN: 0000996205
Attorney, Agent or Firm:
Yukio Ono
Tomoko Inazumi
Kadowaki Manabu