Title:
経口用量の薬学的プロダクトにおけるカプセル化のための粒子の流動化
Document Type and Number:
Japanese Patent JP2006525921
Kind Code:
A
Abstract:
Encapsulated oral dosage pharmaceutical products are produced utilizing a system including a hopper and a dosator, where the hopper receives particles having irregular geometries and sizes greater than about 100 mum for delivery to the dosator. A gaseous fluid is directed into the hopper to fluidize particles within the hopper so as to minimize or eliminate the formation of voids within the bed of particles disposed within the hopper. The fluidization of the particles within the hopper maintains a substantially continuous and uniform flow of particles from the hopper to the dosator, which results in the formation of encapsulated products with desirable weights and particle size distributions.
Inventors:
Shojaei Amir H.
Quivalo Benjamin Thomas
Ibrahim Scott A.
Quivalo Benjamin Thomas
Ibrahim Scott A.
Application Number:
JP2006513374A
Publication Date:
November 16, 2006
Filing Date:
May 12, 2004
Export Citation:
Assignee:
Shire Laboratories, Inc.
International Classes:
B65B1/06; A61J3/06; A61J3/07; A61K9/48; A61K9/50; A61K31/46; A61P25/08; B65B1/38
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Kenji Saito
Kakehi Yuro
Kenji Saito