To obtain a liquid crystal material of the subject derivative having good chemical, photochemical and thermal stabilities, good stability for electric field, short response time, low threshold potential and high contrast.

The derivative is represented by formula (1) (wherein, R is a 1-12C alkyl or alkoxy, a 2-12C alkenyl or alkenyloxy, or the like; Y1 and Y2 are each independently F or H; Z is O(CH2)3, or the like; A is trans-1,4-cyclohexylene, a fluorine-substituted 1,4-phenylene, or the like; X is a 1-6C alkyl or alkoxy, a 2-6C alkenyl, alkenyloxy or alkoxyalkyl, CH=CF2, or the like.). A liquid crystal mixture comprises the derivative.