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Title:
心血管疾患患者(CVD)および糖尿病患者における体重を減らすための、ω3脂肪酸および抗肥満剤を含む製剤
Document Type and Number:
Japanese Patent JP2014505730
Kind Code:
A
Abstract:
Combinations of one or more anti-obesity drugs with mixtures of an omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight comprised of a combination of Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DP A) and Docosahexaenoic acid (DHA) in a weight ratio of EPA: DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA comprise about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition are taught. EPA + DHA are about 80% of the total formulation and about 89% of the total omega 3 fatty acid content of the composition. The formulation may further contain specific amounts of arachidonic acid (AA) and of omega-3 fatty acids having 18 carbon atoms, including one or more of stearidonic acid (SDA) and alpha-linolenic acid (ALA). The application further teaches methods of administering such combinations, and is directed towards unit dosages of such combinations for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics.

Inventors:
Jakowski George
Max Winnie Rachel
Shake Nisar
Yanta Jason
Shini-Kurs Valerie
Application Number:
JP2013554540A
Publication Date:
March 06, 2014
Filing Date:
February 14, 2012
Export Citation:
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Assignee:
Pivotal Therapeutics, Inc.
International Classes:
A61K31/202; A61K9/06; A61K9/08; A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61K31/232; A61K31/44; A61K31/454; A61K31/685; A61K45/00; A61K47/22; A61P3/04; A61P3/06; A61P3/10; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P43/00
Domestic Patent References:
JP2009521214A2009-06-04
JP2008540393A2008-11-20
JP2009515815A2009-04-16
JP2009520824A2009-05-28
JP2008524120A2008-07-10
Foreign References:
EP2085089A12009-08-05
Other References:
JPN5014004296; 'OMEGABRITE' CONSUMERLAB.COM [ONLINE] , 20080525
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto