Title:
疎水性薬剤の上昇した生物学的利用性を提供する製剤
Document Type and Number:
Japanese Patent JP2006507309
Kind Code:
A
Abstract:
The present invention provides a drug formulation and a dosage form. The drug formulation works to increase the bioavailability of hydrophobic drugs delivered to the gastro-intestinal tract ("GI tract") of a desired subject. The drug formulation of the present invention is formulated as a self-emuslifying nanosuspension, which forms an emulsion in-situ upon introduction to an aqueous environment. The dosage form of the present invention may be formed using various different materials and may be configured to deliver the drug formulation of the present invention to the GI tract of a subject using any desired mechanism. A controlled release dosage form according to the present invention may be designed to deliver the drug formulation of the present invention at a desired rate over a desired period of time. If designed as a controlled release dosage form, the dosage form of the present invention may be an osmotic dosage form.
More Like This:
Inventors:
Dong, Liang Shi
Zao, Ruiping
Wong, Patrick S. L
Zao, Ruiping
Wong, Patrick S. L
Application Number:
JP2004550348A
Publication Date:
March 02, 2006
Filing Date:
October 31, 2003
Export Citation:
Assignee:
Alza Corporation
International Classes:
A61K9/16; A61K9/00; A61K9/107; A61K9/12; A61K31/57; A61K47/12; A61K47/34; A61P35/00; A61K9/14; A61K9/51
Attorney, Agent or Firm:
Heikichi Odashima